The entrepreneurial incubation platform is a new type of business incubator that connects and empowers bilateral markets through the Internet， and can optimize the allocation of supply and demand resources. Based on the empowerment theory， it used the case study method taking the Zhubajie as the research object， discussed how the entrepreneurial incubation platform promoting the process of resource matching between resource supply and demand from the research perspective of empowerment mechanism design theory. It finds that the enabling mechanism of the entrepreneurial incubation platform promotes the matching of resources between the supply and demand sides optimally. Among them， the structural empowerment mechanism stimulates the willingness to allocate resources； the resource enabling mechanism creates the conditions for allocation of resources； the data empowerment mechanism enhances the efficiency of resource allocating. It constructs the theoretical model of the empowerment mechanism of entrepreneurial incubation platform to promote the optimization of resource allocation， which has important theoretical value and practical significance for high-quality development of entrepreneurial incubation platform.